Part XVIIC - National out-of-hours formulary

THE FORMULARY CORE DRUG LIST

The following National Out-of-Hours Core Formulary contains the minimum list of drugs that patients should be able to access. Exact mechanisms for the provision of these drugs should be decided locally, taking into account existing treatment protocols. (England only. At the time of going to press the Welsh Ministers had not adopted the formulary)

Guidance and information on template PGDs can be found on the website:http://www.pgd.nhs.uk/

Drug

Comment

Oral

 
 
Child
Adult
Injectable
Other
 

ANALGESIA

 
 
 
 

Codeine or equivalent

Oral formulations to be supplied as a full course to appropriately treat the presenting condition.
Codeine preferred as it has a dual role for pain relief and diarrhoea.
 
Y
 
 

Diamorphine

Diamorphine is preferred for its use in both cardiac pain and palliative care.
 
 
Y
 

Non Steroidal Anti-Inflammatory Drug (NSAID)

Oral formulations to be supplied as a full course to appropriately treat the presenting condition. The exact preparation(s) should be decided after local negotiation.
Intramuscular injection of a NSAID may avoid the need for controlled drug use.
Y
Y
Y
 

Paracetamol

Supply as a full course to appropriately treat the presenting condition.
Y
Y
 
 

ASTHMA

Inhaled Ipratropium

Supply as a full course to appropriately treat the presenting condition.
 
 
 
Y

Inhaled Salbutamol or equivalent

Supply as a full course to appropriately treat the presenting condition.
 
 
 
Y

Prednisolone

Oral formulations to be supplied as a full course to appropriately treat the presenting condition. Soluble tablets may be preferable for dual use in children and adults.
Y
Y
 
 

Spacer Device

Or nebuliser device.
 
 
 
Y

CARDIAC EMERGENCIES

Adrenaline/Epinephrine

Strength/formulation suitable for treatment of cardiac arrest.
 
 
Y
 

Aspirin

For use in all patients with suspected Myocardial Infarction unless contraindicated or already taken.
 
Y
 
 

Atropine

For use in cardiac emergencies.
 
 
Y
 

Diamorphine

 
 
 
Y
 

Furosemide

Supply as a full course to appropriately treat the presenting condition. Full course of oral tablets is expected to be 7 days maximum.
 
Y
Y
 

Glyceryl Trinitrate Sub-lingual

Supply as a full course to appropriately treat the presenting condition.
 
Y
 
 

ALLERGY/ANAPHYLAXIS

Adrenaline/Epinephrine

Strength/formulation suitable for treatment of anaphylaxis.
 
 
Y
 

Hydrocortisone

Hydrocortisone sodium succinate can be used for anaphylaxis, asthma and hypoadrenalism.
 
 
Y
 

Chlorphenamine

Supply as a full course to appropriately treat the presenting condition.
Y
Y
Y
 

Non-Sedating Antihistamine

Supply as a full course to appropriately treat the presenting condition. Choice of preparation to be decided locally.
 
Y
 
 

DIABETIC EMERGENCIES

Glucagon Injection

Current recommendation is for both Glucose IV and Glucagon to be carried. Children may not respond to Glucagon so are more likely to need glucose. Patients not responding should be admitted.
 
 
Y
 

Glucose

 
 
Y
 

OPIOID OVERDOSE

Naloxone

Any patient with an opioid overdose should be admitted to hospital, as repeated doses may be required.
 
 
Y
 

GASTROINTESTINAL

Antacid

Supply as a full course to appropriately treat the presenting condition taking into account manufacturers' pack sizes.
 
Y
 
 

Domperidone

Supply as a full course to appropriately treat the presenting condition (see also metoclopramide).
 
Y
 
 

Glycerol Suppositories

Included for immediate symptom relief (may be suitable for use by other healthcare professionals).
 
 
 
Y

Anti-Spasmodic Agent

Supply as a full course to appropriately treat the presenting condition.
 
Y
 
 

Loperamide

Supply as a full course to appropriately treat the presenting condition.
 
Y
 
 

Metoclopramide

Included as there is no parenteral formulation of domperidone
 
 
Y
 

Oral Rehydration Sachets

Supply as a full course to appropriately treat the presenting condition.
Y
 
 
 

Phosphate Enema

Included for immediate symptom relief (may be suitable for use by other healthcare professionals).
 
 
 
Y

Prochlorperazine

Oral formulations to be supplied as a full course to appropriately treat the presenting condition.
 
Y
Y
Y
 

PSYCHIATRIC EMERGENCIES/CNS

 
 
 
 

Diazepam

Supply as a full course to appropriately treat the presenting condition. Course length to be decided locally taking into account local policies and guidelines. Small quantities may be more appropriate. An appropriate rectal formulation to be included.
Y
Y
Y
Y

Haloperidol

Supply as a full course to appropriately treat the presenting condition. May also be used for treatment of severe nausea and vomiting.
 
Y
Y
 

Procyclidine

Supply as a full course to appropriately treat the presenting condition.
 
Y
Y
 

OBSTETRIC AND GYNAECOLOGY

Levonorgestrel 1500

Full course to be supplied - included as current evidence suggests early treatment is appropriate.
 
Y
 
 

Syntometrine Injection

Rarely used but essential to have available for intra or post partum obstetric emergencies. Special storage arrangements may be necessary.
 
 
Y
 

PALLIATIVE CARE DRUGS

Diamorphine

 
 
 
Y
 

Cyclizine

It is expected that these drugs would be part of a special tamper proof palliative care pack that would be locally available. Local discussions will be necessary to determine appropriate access. The quantities supplied should be enough to allow appropriate symptom relief until formal review by palliative care team or General Practitioner.
 
 
Y
 

Dexamethasone

 
Y
 
 

Hyoscine Butylbromide

 
 
Y
 

Ketorolac/Diclofenac

 
 
Y
 

Methotrimeprazine/Levomepromazine

 
 
Y
 

Midazolam

 
 
Y
 

LOCAL ANTIBIOTIC CHOICE

Following local discussion, antibiotics should be made available to appropriately treat the conditions listed below.
Choice of preparation(s) should take into account local resistance patterns.

Cellulitis and other skin infections

Supply as a full course to appropriately treat the presenting condition. Choice of preparation(s) should be made after local discussion taking into account local resistance patterns.
Y
Y
 
 

Respiratory infections

Y
Y
 
 

Upper respiratory tract infections

Y
Y
 
 

Urinary tract infections

Y
Y
 
 

INFECTION

Bacterial conjunctivitis

Supply as a full course to appropriately treat the presenting condition. Choice of preparation(s) should be made after local discussion taking into account local resistance patterns.
 
 
 
Y

Candidiasis (Topical)

Included for immediate symptom relief.
 
 
 
Y

Herpes Zoster

Supply as a full course to appropriately treat the presenting condition. Choice of preparation to be decided locally. Included as current evidence suggest early treatment is appropriate.
 
Y
 
 

Benzylpenicillin

For immediate treatment of meningococcal meningitis or septicaemia. Patients with suspected meningitis should be transferred to hospital urgently.
 
 
Y
 

MISCELLANEOUS

Sodium chloride for injection/ infusion

Also to include IV giving set and canula
 
 
Y
 

Water for injection

For dissolving injectable drugs.
 
 
Y
 

Blood glucose testing sticks

Use where diagnosis cannot safely wait e.g. to identify patients who have urgent treatment needs or who should be admitted to hospital.
 
 
 
Y

Urine testing sticks

Use where diagnosis cannot safely wait e.g. to identify patients who have urgent treatment needs or who should be admitted to hospital.
 
 
 
Y

DRUGS WHERE SPECIAL ARRANGEMENTS MAY BE APPROPRIATE

Oxygen

It may be appropriate for some organisations to keep a supply of oxygen. Alternatively, local discussion and specific arrangements will need to be made for the delivery of oxygen.
 
 
 
 
 
Issue: June 2010